Potentially Inappropriate Medication (PIM) Prescribing According to Beers Criteria among Elderly Outpatients at Pasar Minggu Hospital, Jakarta
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Elderly patients generally have physiological changes that cause multipathological conditions, so they require several drugs to treat these conditions, it is necessary to evaluate the use of drugs to optimize the treatment of geriatric patients. Beers Criteria 2019 is a criteria that is commonly used to present Potentially Inappropriate Medication (PIM). This study aimed to examine the inaccuracy of prescription drugs in the elderly using Beer's criteria 2019. This research is an observational analytic study with a cross-sectional descriptive design. The Beer's 2019 criteria classify PIM into five categories. Data were taken retrospectively as many as 847 prescriptions met the inclusion criteria at the Pasar Minggu Hospital Outpatient Polyclinic. Data were analysed by Univariate and Bivariate. The results showed that from 847 prescriptions for geriatric patients, there are 160 prescriptions for geriatric patients who experienced PIM (18.89%). Percentage of PIM incidents by category; namely, category 1 was 29.17%, category 2 was 6.77%, category 3 was 44.79%, category 4 was 16.67%, and category 5 was 2.60%. The results of the analysis showed that there was a significant relationship between the number of drugs and Heart Failure and CAD with the incidence of PIM with a p value of 0.000 and 0.035. DM and Heart Failure are 2 diseases that significantly influence the incidence of PIM. This study concludes that the elderly are at risk for receiving potentially inappropriate medications.
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World Health Organization. Decade of healthy ageing: baseline report. World Health Organization; 2021.
Indonesia. Badan Pusat Statistik. Statistik Penduduk Lanjut Usia 2022. Jakarta: Direktorat Statistik Kesejahteraan Rakyat; 2022.
Pazan F, Wehling M. Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences. Eur Geriatr Med. 2021;12:443–452. doi: 10.1007/s41999-021-00479-3.
Almeida TA, Reis EA, Pinto IVL, Ceccato MDGB, Silveira MR, Lima MG, et al. Factors associated with the use of potentially inappropriate medications by older adults in primary health care: An analysis comparing AGS Beers, EU (7)-PIM List, and Brazilian Consensus PIM criteria. Research in Social and Administrative Pharmacy. 2019;15(4):370—377. doi: 10.1016/j.sapharm.2018.06.002.
Fauziah H, Mulyana R, Martini RD. Polifarmasi Pada Pasien Geriatri. Hum Care J. 2020;5(3):804-812. doi: 10.32883/hcj.v5i3.796.
Darmawan E, Ahmad H, Perwitasari DA, Kusumawardani N. Pharmacist intervention can reduce the potential use of inappropriate drugs medications in Indonesian geriatric patients. J Appl Pharm Sci. 2020; 10(1):088–095. doi: 10.7324/JAPS.2020.101012.
Wulansari A, Wiedyaningsih C, Probosuseno P. Potentially Inappropriate Medication (PIM) pada Pasien Geriatri Rawat Inap di RSUD Dr. H. Moch. Ansari Saleh Banjarmasin. Majalah Farmaseutik. 2021;19(1):91-98. doi: 10.22146/farmaseutik.v19i1.70420.
Bhagavathula AS, Vidyasagar K, Chhabra M, Rashid M, Sharma R, Bandari DK, Fialova D. Prevalence of polypharmacy, hyperpolypharmacy and potentially inappropriate medication use in older adults in India: A systematic review and meta-analysis. Frontiers in pharmacology. 2021;12:685518. doi: 10.3389/fphar.2021.685518.
Handayani U. Kajian Beers Criteria Pada Pasien Geriatri Rawat Inap di RSUD dr. Soekardjo Kota Tasikmalaya [Doctoral dissertation]. STIKes BTH Tasikmalaya; 2018.
Rumi A, Tahir MT, Ilham M. Identifikasi Potentially Inappropriate Medication (PIM) Melalui Beers Criteria pada Pasien Geriatri Rawat Inap di Ruangan Seroja dan Flamboyan RSUD Undata Provinsi Sulawesi Tengah. Media Publikasi Promosi Kesehatan Indonesia (MPPKI). 2023;6(1):51-58. doi: 10.56338/mppki.v6i1.2531.
Sasfi SM, Untari EK, Rizkifani S. Evaluasi Pola Peresepan Pasien Geriatri di RSUD Dr. Soedarso Pontianak Berdasarkan Beers Criteria. Indonesian Journal of Clinical Pharmacy. 2022;11(2):95-104. doi: 10.15416/ijcp.2022.11.2.95.
Indonesia. Kemenkes RI KK. Buku Kesehatan Lanjut Usia. Jakarta: Kementerian Kesehatan Republik Indonesia; 2019.
2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. Journal of the American Geriatrics Society. 2019. doi: 10.1111/jgs.15767.
Mulyani T, Rukminingsih F. Evaluasi Peresepan Pada Pasien Geriatri Di Klinik Penyakit Dalam Instalasi Rawat Jalan RSUD KRMT Wongsonegoro Semarang. Jurnal Riset Kefarmasian Indonesia. 2020;2(2):89-96. doi: 10.33759/jrki.v2i2.82.
Julaiha S. Identifikasi potentially inappropriate medications (PIMs) berdasarkan kriteria STOPP START pada pasien geriatri rawat inap di RS Advent Bandar Lampung. Jurnal Analis Kesehatan. 2018;7(1):657-665. doi: 10.26630/jak.v7i1.912.
Isnaini RD, Darmawan E, Dewi FY. The Function of Recommendation of a Pharmacists in Reduce PIMs (Potentially Inappropriate Medications) of Geriatric Patients at The General Hospital Dr. Moewardi Surakarta. Pharmacology, Medical Reports, Orthopedic, and Illness Details (COMORBID). 2022;1(2):9-18. Doi: 10.55047/comorbid.v1i2.81.
Viviandhari D, Nurhasnah N, Sakinah, RN, Wulandari D. A Comparison of Potentially Inappropriate Medications Identification Using Beers and STOPP Criteria in Hospitalized Geriatric Patients in Jakarta. Indonesian Journal of Clinical Pharmacy. 2022;11(2):105-115. doi: 10.15416/ijcp.2022.11.2.105.
Cahyaningsih I, Amaliya N. Kajian resiko penggunaan obat yang harus digunakan dengan hati-hati pada pasien geriatri dengan diagnosis gangguan saraf berdasarkan Beers Criteria. Media Farm. 2019;16(1):51-62. doi: 10.12928/mf.v16i1.12947.
Astuti R, Susanti R. Detection of Potentially Inappropriate Medication in Elderly Outpatient Based on The Beer's Criteria 2019. Pharmacy & Pharmaceutical Sciences Journal/Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia. 2022;9(1):82-91. doi: 10.20473/jfiki.v9i12022.82-91.
Tian F, Chen Z, Zeng Y, Feng Q, Chen X. Prevalence of use of potentially inappropriate medications among older adults worldwide: a systematic review and meta-analysis. JAMA network open. 2023;6(8):e2326910-e2326910. doi: 10.1001/jamanetworkopen.2023.26910
Levy A, El-Hage W, Bennabi D, Allauze E, Bouvard A, Camus V, et al. Occurrence of side effects in treatment-resistant depression: role of clinical, socio-demographic and environmental characteristics. Frontiers in psychiatry. 2021;12:795666. doi: 10.3389/fpsyt.2021.795666.
Bergemann N, Clement H, Conca A, Deckert J, Domschke K, Eckermann G, et al. Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017. Pharmacopsychiatry. 2018;51(01/02):9-62. doi: 10.1055/s-0043-116492.
Widiasari KR, Wijaya IMK, Suputra PA. Diabetes Melitus Tipe 2: Faktor Risiko, Diagnosis, Dan Tatalaksana. Ganesha Medicina. 2021;1(2):114-120. doi: 10.23887/gm.v1i2.40006.
Toombs AR, Jung JY, White. ND. Benzodiazepine Use and Cognition in the Elderly. American Journal of Lifestyle Medicine. 2018;12(4):295-297. doi: 10.1177/1559827618767381.
Roy PJ, Weltman M, Dember LM, Liebschutz J, Jhamb M, HOPE Consortium. Pain management in patients with chronic kidney disease and end-stage kidney disease. Current opinion in nephrology and hypertension. 2020;29(6):671-680. doi: 10.1097/MNH.0000000000000646.
Masi S, Uliana M, Gesi M, Taddei S, Virdis A. Drug-induced hypertension: Know the problem to know how to deal with it. Vascular pharmacology. 2019;115:84-88. doi: 10.1016/j.vph.2019.02.002.
Hutasuhut MI. Evaluasi Penggunaan Obat pada Ruang Gawat Darurat di RSUD Dr. Pirngadi Medan [Doctoral dissertation]. Universitas Sumatera Utara; 2021.
Isnenia I. Penggunaan Non-Steroid Antiinflamatory Drug dan Potensi Interaksi Obatnya Pada Pasien Muskuloskeletal. Pharmacy Journal Indonesia. 2020;6(1):47-55. doi:10.21776/ub.pji.2020.006.01.8.
Fleet JL, Dixon SN, Kuwornu PJ, Dev VK, Montero-Odasso M, Burneo J, et al. Gabapentin dose and the 30-day risk of altered mental status in older adults: A retrospective population-based study. PLoS One. 2018;13(3):1-14. doi:10.1371/journal.pone.0193134.
Emmett SR, Hill N, Dajas F, Dajas-Bailador F. Clinical Pharmacology for Prescribing. USA: Oxford University Press; 2019.
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