Potensi Fraksi Etil Asetat Ekstrak Daun Gambir (Uncaria gambir Roxb.) sebagai Antihiperlipidemia
VOLUME 5, NOMOR 1, FEBRUARI 2015
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March 13, 2020
February 17, 2015
February 17, 2015
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Yunarto N, Elya B, Konadi L. Potensi Fraksi Etil Asetat Ekstrak Daun Gambir (Uncaria gambir Roxb.) sebagai Antihiperlipidemia. jki [Internet]. 2015 Feb. 17 [cited 2026 Apr. 3];5(1):1-10. Available from: https://jkefarind.com/index.php/jki/article/view/2959
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1. Global atlas on cardiovascular disease prevention and control. Geneva: World Health Organization; 2013.
2. Mullis RM, Blair SN, Aronne LJ. Obesity, a worldwide epidemic related to heart disease and stroke. Circulation. 2004;110:484-8.
3. Septianggi FN, Mulyati T, Sulistya H. Hubungan asupan lemak dan asupan kolesterol dengan kadar kolesterol total pada penderita jantung koroner rawat jalan di RSUD Tugurejo Semarang. Jurnal Gizi Unimu. 2013;2(2):13-20.
4. Fadecko J, Singh RB, Chaithiraphan S, Vargova V, Tomlinson B, De Meester F, et al. Clinical manifestations of adverse Jurnal Kefarmasian Indonesia. 2015;5(1):1-10 10 effects of statins, oxidative stress and possible role of antioxidants in prevention. The Open Nutraceuticals Journal. 2010;3:154-65.
5. Kobayashi M, Unno T, Suzuki Y, Nozawa A, Sagesaka Y, Kakuda T, et al. Heat-epimerized tea catechins have the same cholesterol-lowering activity as green tea catechins in cholesterol-fed rats. Bioscience Biotechnology Biochemistry. 2005;69:2455-8.
6. Kassim MJ, Hussin MH, Achmad A, Dahon NH, Suan TK, Hamdan HS. Determination of total phenol, condensed tannin and flavonoid contents and antioxidant activity of Uncaria gambir extracts. Majalah Farmasi Indonesia. 2011;22(1):50-9.
7. Indonesia. Farmakope Herbal Indonesia Edisi I, Jakarta. Departemen Kesehatan; 2008.
8. Sensitive determination of catechins in tea by HPLC. Sunnyvale: Dionex Corporation; 2013.
9. Lucida H, Rustini, Saufitri D, Dachriyanus. Formulation of anti-plaque toothpaste from standardized gambir extract and its antimicrobial activity. Jurnal Farmasi Indonesia. 2010;5(2):70 - 7.
10. USA. United Book Press.United States Pharamcopeia-30. Baltimore. United States Pharmacopeial Convention; 2007.
11. Feldsine P, Abeyta C, Andrews WH. International methods committee guidelines for validation of qualitative and quantitative food microbiological official methods of analysis. J AOAC Int. 2002 Sep-Oct;85(5):1187-200.
12. Murray RK, Granner DK, Rodwell VW. Harper’s Illustrated Biochemistry. New York: The Mc Graw-Hill Companies; 2006.
13. Carvajal ZO, Waliszewski SM, Barradas DM, Orta FZ, Hayward JPM, Nolasco HC, et al. The consumption of Hibiscus sabdariffa dried calyx ethanolic extract reduced lipid profile in rats. Plant Food Hun Nutr. 2005 Dec;60(4):153-9.
14. Ikeda I. Multifunctional effects of green tea catechins on prevention of the metabolic syndrome. Asia Pacific Journal of Clinical Nutrition. 2008;17(1):273-4.
15. Delaney CAJ. Exotic Companion Medicine Handbook for Veterinarians. Florida: Zoological Education Network; 2008.
16. Dulloo AG, Seydoux J, Girardier L. Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. International Journal Obesity Relation Metabolism Disorder. 2000;24:252-8.
17. Mustofa UE. Effect of green tea and green tea rich with catechin on blood glucose levels, serum lipid profile and liver and kidney functions in diabetic rats. Jordan Journal of Biological Sciences. 2014;7(1):7-12.
18. Tomkin GH, Owens D. LDL as a cause atherosclerosis. The Open Atherosclerosis & Thrombosis Journal. 2012;5:13-21.
19. Kim A, Chiu A, Barone MK, Avino D, Wang F, Coleman CI, et al. Green tea catechins decrease total and low-density lipoprotein cholesterol: a systematic review and meta-analysis. Journal of the American Dietic Association. 2011;111(11):1720-9.
20. Tsalissavrina I, Wahono D, Handayani D. Pengaruh pemberian diet tinggi karbohidrat dibandingkan diet tinggi lemak terhadap kadar trigliserida dan HDL darah pada Rattus novergicus galur wistar. Jurnal Kedokteran Brawijaya. 2006;22(2):80-9. 21. Velayutham P, Babu A, Liu D. Green tea catechins and cardiovasculer health: An up dare. Current Medicinal Chemistry. 2008;15(18):1840-50.
2. Mullis RM, Blair SN, Aronne LJ. Obesity, a worldwide epidemic related to heart disease and stroke. Circulation. 2004;110:484-8.
3. Septianggi FN, Mulyati T, Sulistya H. Hubungan asupan lemak dan asupan kolesterol dengan kadar kolesterol total pada penderita jantung koroner rawat jalan di RSUD Tugurejo Semarang. Jurnal Gizi Unimu. 2013;2(2):13-20.
4. Fadecko J, Singh RB, Chaithiraphan S, Vargova V, Tomlinson B, De Meester F, et al. Clinical manifestations of adverse Jurnal Kefarmasian Indonesia. 2015;5(1):1-10 10 effects of statins, oxidative stress and possible role of antioxidants in prevention. The Open Nutraceuticals Journal. 2010;3:154-65.
5. Kobayashi M, Unno T, Suzuki Y, Nozawa A, Sagesaka Y, Kakuda T, et al. Heat-epimerized tea catechins have the same cholesterol-lowering activity as green tea catechins in cholesterol-fed rats. Bioscience Biotechnology Biochemistry. 2005;69:2455-8.
6. Kassim MJ, Hussin MH, Achmad A, Dahon NH, Suan TK, Hamdan HS. Determination of total phenol, condensed tannin and flavonoid contents and antioxidant activity of Uncaria gambir extracts. Majalah Farmasi Indonesia. 2011;22(1):50-9.
7. Indonesia. Farmakope Herbal Indonesia Edisi I, Jakarta. Departemen Kesehatan; 2008.
8. Sensitive determination of catechins in tea by HPLC. Sunnyvale: Dionex Corporation; 2013.
9. Lucida H, Rustini, Saufitri D, Dachriyanus. Formulation of anti-plaque toothpaste from standardized gambir extract and its antimicrobial activity. Jurnal Farmasi Indonesia. 2010;5(2):70 - 7.
10. USA. United Book Press.United States Pharamcopeia-30. Baltimore. United States Pharmacopeial Convention; 2007.
11. Feldsine P, Abeyta C, Andrews WH. International methods committee guidelines for validation of qualitative and quantitative food microbiological official methods of analysis. J AOAC Int. 2002 Sep-Oct;85(5):1187-200.
12. Murray RK, Granner DK, Rodwell VW. Harper’s Illustrated Biochemistry. New York: The Mc Graw-Hill Companies; 2006.
13. Carvajal ZO, Waliszewski SM, Barradas DM, Orta FZ, Hayward JPM, Nolasco HC, et al. The consumption of Hibiscus sabdariffa dried calyx ethanolic extract reduced lipid profile in rats. Plant Food Hun Nutr. 2005 Dec;60(4):153-9.
14. Ikeda I. Multifunctional effects of green tea catechins on prevention of the metabolic syndrome. Asia Pacific Journal of Clinical Nutrition. 2008;17(1):273-4.
15. Delaney CAJ. Exotic Companion Medicine Handbook for Veterinarians. Florida: Zoological Education Network; 2008.
16. Dulloo AG, Seydoux J, Girardier L. Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. International Journal Obesity Relation Metabolism Disorder. 2000;24:252-8.
17. Mustofa UE. Effect of green tea and green tea rich with catechin on blood glucose levels, serum lipid profile and liver and kidney functions in diabetic rats. Jordan Journal of Biological Sciences. 2014;7(1):7-12.
18. Tomkin GH, Owens D. LDL as a cause atherosclerosis. The Open Atherosclerosis & Thrombosis Journal. 2012;5:13-21.
19. Kim A, Chiu A, Barone MK, Avino D, Wang F, Coleman CI, et al. Green tea catechins decrease total and low-density lipoprotein cholesterol: a systematic review and meta-analysis. Journal of the American Dietic Association. 2011;111(11):1720-9.
20. Tsalissavrina I, Wahono D, Handayani D. Pengaruh pemberian diet tinggi karbohidrat dibandingkan diet tinggi lemak terhadap kadar trigliserida dan HDL darah pada Rattus novergicus galur wistar. Jurnal Kedokteran Brawijaya. 2006;22(2):80-9. 21. Velayutham P, Babu A, Liu D. Green tea catechins and cardiovasculer health: An up dare. Current Medicinal Chemistry. 2008;15(18):1840-50.











